The standard Drush command for clearing Drupal's cache looks like this:

drush cache-clear all

(You can also use the shortened alias cc like this: drush cc all)

Several months back, I released a module to drupal.org, called Template Picker.

Every day, millions of nodes are saved. It happens every time content is created, migrated, or updated. It's probably the most common content management task in Drupal.

So what are you trying to say?