There are a lot of modules for Drupal. One of them, Domain Access, enables multiple different domains on a single Drupal site and allows setting different variable values for each domain. Another of them, Internationalization, allows different variable values for each language. What was missing was a mechanism to handle that variables consistently and then allowing to mix these two 'variable realms' setting specific values for specific combinations of Domain and Language.

• Drupal
• Domain Access
• Variable
• Internationalization